Hair
Transplantation to the Eyebrow, Eyelashes, and Other
Parts of the Body
By Jeffrey
S. Epstein, MD and Marcelo
Gandleman, MD
Synopsis
Introduction
Reconstruction of Eyebrows
and Eyelashes
History
Etiology
The Consultation
Designing and Restoration
Surgical Technique
Reconstruction of the Sideburn,
Moustache, and Beard
Chest Hair Transplantation
Restoration of The Pubic Escutcheon
Authors:
Marcelo Gandleman, MD
Private Practice, Brazil
Jeffrey Epstein, MD, FACS
Associate Clinical Professor, University of Miami College
of Medicine,
Department of Otolaryngology
SYNOPSIS:
Since its earliest applications, hair transplantation
has been utilized for treating not only the scalp in
pattern baldness, but also other parts of the body,
commencing with eyebrow reconstruction. The earliest
micrografts were applied to the eyebrow, more than 30
years before their application to the scalp became the
standard of care.
While the popularity of hair transplantation today is
largely a testament to the quality of results attainable
for the treatment of male and female pattern hair loss,
it can, and is, applied to a number of other areas.
The principle behind transplanting these areas is the
same- once transplanted, the hairs continue to grow
due to the phenomenon of donor dominance. Presented
is a review of the role and technique of hair transplantation
to the eyebrows and eyelids, chest, beard and moustache,
and pubic escutcheon
INTRODUCTION
Since its earliest applications, hair transplantation
has been utilized for treating not only the scalp in
pattern baldness, but also other parts of the body,
commencing with eyebrow reconstruction. The earliest
micrografts were applied to the eyebrow, more than 20
years before their application to the scalp became the
standard of care.(1-3)
While the popularity of hair transplantation today is
largely a testament to the quality of results attainable
for the treatment of male and female pattern hair loss,
it can, and is, applied to a number of other areas.
The principle behind transplanting these areas is the
same- once transplanted, the hairs continue to grow
due to the phenomenon of donor dominance. What follows
is a review of the role and technique of hair transplantation
to the eyebrows and eyelids, chest, beard and mustache,
and pubic escutcheon.
RECONSTRUCTION
OF EYEBROWS AND EYELASHES
Bald people are considered normal and healthy human
beings, and have the option of staying bald. However,
madarosis, the absence of eyebrows or eyelashes, can
be an unnatural, humiliating characteristic, attracting
curiosity, causing social discomfort, and adversely
affecting self-esteem and professional and romantic
relationships. It is said that the eyes are the window
to the soul, reflecting our state of mind. We actually
believe that eyebrows create the expressions attributed
to the eyes, such as surprise, fear, and rage, and that
eyelashes are responsible for the sensual look, with
blinking Mother Nature’s way of flirting.
On a functional basis, the absence of eyebrows and eyelashes
makes the eyes more vulnerable. Eyebrows keep forehead
perspiration away from eyes, and with squinting, facilitate
the blocking of bright sun. Eyelashes keep dust and
foreign bodies from the eyes, and initiate the blink
reflex.
In restoring anatomy, eyebrow and eyelash reconstruction
surgery restores function, improves appearances, and
elevates patients’ self esteem.
HISTORY
In 1914, Krusius rebuilt eyelashes harvesting scalp
grafts with small punches, then transplanting them to
the ciliary border with the same punch.(4) Knapp in
1917 developed the technique of inserting a free strip
graft from the eyebrow along the eyelid border.(5) Sasagawa
in 1930 reported the method of hair shaft insertion.(1)
Fujita in 1953 reconstructed eyebrows by punctiform
hair grafting using an injection needle.(6-8) In 1980,
Marritt transplanted follicular roots extracted from
the periphery of 4 mm circular punches, inserting them
in the eyelid border with a needle.(9-11)
Other described methods of eyebrow reconstruction include
free or pedicled strip hair grafts from the scalp or
the contralateral eyebrow (12), temporal artery island
flaps (13, 14), and punch hair transplantation.(15)
For eyelid reconstruction, other described methods include
strip grafts from the eyebrows, pedicled flaps from
the eyebrows, and strip sideburn grafts.(16)
At present, we use single, and occasionally double hair
grafts obtained through follicular unit dissection,
harvested from the scalp.
ETIOLOGY:
Loss of eyebrows and eyelashes can have a number of
etiologies. The most common is that from trauma, such
as avulsions and burns, and complications from tattooing
and infections, where scarring results in areas of alopecia.
The recent popularity of body piercing has been associated
with cases of alopecic scarring following infection
of piercing channels. Scarring from tumor surgery, radiation
therapy, and inadvertently placed incisions of direct
browlift surgery can all produce alopecia. Long term
electrolysis or plucking, or overzealous laser hair
removal can result in thinned or absent eyelashes or
eyebrows. Trichotillomania, an obsessive-complulsive
disorder characterized by repeated hair pulling over
a series of years, and a variety of dermatologic diseases
(17) must also be considered and, if necessary, treated.
Finally, endocrinopathies, such as hypothryodism , which
can be treated, and congenital aplasia are also common
causes.
THE
CONSULTATION:
The role of the consultation is patient education and
assessment of the patient’s appropriateness for
surgery. It is a time for the surgeon to provide realistic
expectations, as well as to investigate for potential
etiologies of the hair loss, learn the goals of the
patient, and assure that there are no contraindications
for surgery. In many cases, because the patient does
not consider this procedure as “real” surgery,
there is a risk that some of the medical history will
not be provided.(18) A thorough medical history and
examination should be focused on finding contributing
etiologies to the hair loss.
While rare in the eye region, individuals prone to excessive
scarring or to keloid formation should be advised of
the risk, and closely watched in the post-procedure
period. The patient must be completely recovered from
dermatologic diseases such as discoid lupus and alopecia
areata, including obtaining clearance for the procedure
by a dermatologist. Psoriasis is not a contraindication
for surgery.(18,19)
Hypertension and diabetes, while not contraindications
for surgery, should be under clinical control. Cases
of untreated or poorly treated hypothyroidism should
be evaluated by an endocrinologist to reduce the chance
of further loss of eyebrow hair. A patient with trichotillomania
or psychiatric illness should have clearance from a
psychiatrist.
If desired, preoperative screening tests can include
prothrombin and partial thromboplastin times (PT and
PTT), platelet count, and CBC. In nearly all cases,
a thorough history is much more accurate than a battery
of expensive lab tests in detecting any bleeding risks.
If such risks are detected, a bleeding time is probably
the most accurate for objective measurement. Tests for
HIV and hepatitis can be included according to the community’s
standard of care. Because of the risk of graft popping
and hematoma formation, patients are advised to avoid
aspirin and vitamin E for 10 days, and alcoholic beverages
and anti-inflammatories for 3 days prior to surgery.
Vitamin C 1000 to 2000 mgs a day for 10 days may help
reduce bruising.
Patients with permanent makeup of the eyebrows and/or
eyelashes are good candidates for surgical reconstruction.
The tattoo does not interfere with graft integration,
and provides a background shade after surgery, enhancing
the appearance of density. Patients who receive transplants
are advised of the further enhancement that can be achieved
by undergoing permanent makeup to the area.
While not legal in the United States, in most other
countries the implanting of nylon threads for baldness
and other hair reconstruction is legal. Patients with
nylon eyebrow implants usually have a chronic inflammation/infection,
with scar sequelae. Prior to definitive surgery, all
remaining nylon remnants must be removed, and full recovery
from the infection confirmed.
DESIGNING AND
RESTORATION
With the patient seated, the most natural design is
marked out. With the patient’s input, the limits
of the proposed grafting can be altered to provide wider
or narrower, and shorter or longer coverage. Glamorous
or stylish designs are typically avoided, as the goal
is to follow the natural anatomical patterns.
The female eyebrow is typically more cephalic to the
orbital rim, with a mild to moderate arched shape that
is most cephalic at a point superior to the lateral
limbus.(Figure 1) The male eyebrow is typically lower
and less arched, with a straighter appearance, together
with the nose forming a “T”, with the horizontal
limbs composed of the eyebrows and the vertical limb
a line drawn along the midpoint of the nose in its axis.(Figure
2) Attention to the fluctuating direction of growth
of the hairs is essential to help assure a natural appearance.
Medially, the hairs in the natural eyebrow grow vertically
in a cephalic direction, while laterally, the more cephalic
hairs grow somewhat laterally and caudally, while the
more caudal hairs grow somewhat laterally and cephalically,
in a cross-hatched pattern. While it is important to
incorporate these guidelines, the best results are usually
attained when the recipient sites are made such that
the direction of hair growth is not so cephalic or caudal,
but rather more horizontal/lateral. In addition, the
angle of growth from the skin is minimal, so that the
hairs are basically growing flat along the surface,
rather than sticking out from the face.
With the eyelashes, there is much less variation in
direction and angle of growth. The goal is to have the
hairs grow away from the leading edge of the eyelid.
Often the patient needs to use a curler to direct the
hairs in the proper direction of growth. Photographic
documentation of the markings, showing the plan for
restoration, are necessary.(20)
SURGICAL
TECHNIQUE
Preparation and Design
The night before and morning of the procedure, the patient
is to wash the face and hair with an antiseptic soap.
A light meal prior to the procedure is recommended,
especially if the patient is to receive oral sedation.
Our choice of sedation is a benzodiazepine, such as
diazepam, and sometimes a hypnotic like Ambien®
(zolpidem tartrate). In addition, some surgeons prescribe
antibiotics perioperative and for 3 days post-operative.
Local anesthesia of 2% lidocaine with 1:100,000 epinephrine,
in minute amounts, is injected. The use of the Wand®
(Milestone Scientific Inc, Livingston, NJ) can help
reduce the discomfort of injection. Betadine prep is
usually preferable to that done with antiseptics like
chlorhexidene with which there is a risk of corneal
damage.
Donor Material
Once anesthetized, the donor material is excised, either
as a single fusiform shaped strip which is sutured closed,
or extracted as individual follicles using tiny 1 to
1.5 mm punches into the donor area, using the more recently
developed technique of follicular unit extraction and
avoiding the need for sutures. At our earliest surgeries,
we attempted to transplant the most delicate hair of
the nape of the neck or of the temporal region just
behind and/or above the ear, believing that these thinner
hairs would provide a finer, more natural appearance.(21)
With time, it became clear that there is no difference
when slightly thicker hairs are utilized from those
areas or from the mid-occipital region. Some authors
have noted that hairs transplanted to eyebrows, legs,
and potentially other areas of the body may grow with
a diameter smaller than they had in the donor area,
suggesting some role of recipient site dominance. It
has been personally observed that transplanted eyebrow
hair undergoes a type of metaplasia in its new location,
producing a more harmonious and favorable final result.
Dr. William Parsley has measured the diameters of scalp
and eyebrow hairs with an optical micrometer. He demonstrated
that, in Asian patients, scalp hair is actually thicker
than eyebrow hair, while in Caucasians, the opposite
is true- eyebrow hairs have a larger diameter than scalp
hair.(22)
For the eyebrow, the single fusiform-shaped ellipse
of donor tissue need not measure larger than 1 by 3
cms, which should provide at least 250 follicular unit
grafts. This number is usually sufficient for restoring
both eyebrows, and can be adjusted downward if less
work is to be performed. Closure of the donor site is
accomplished with a simple running 3-0 polypropylene
(Prolene; Ethicon Inc, Sommerville, NJ) suture. The
follicular unit grafts will each contain 1, and if the
surgeon deems, 2 hairs. Dissection of each graft is
performed under microscopic visualization so as to assure
the inclusion of a minimal amount of surrounding skin.(23)
For the eyelashes, most surgeons advocate the removal
of virtually all surrounding skin, leaving just the
actual hair and follicle. These eyelash grafts can be
created by stripping away the surrounding skin with
a jeweler’s forceps.
Recipient Sites and Graft Placement
The incisions are made along the markings as close together
as possible. A variety of instruments are available
for this step- a 20 or 21 gauge needle, or a microblade
0.7 or 0.8 mm in size, custom cut from a single edge
razor blade, are appropriate. Direction and angle of
recipient sites should closely parallel the direction
of natural hair growth, to the degree described above.
An average of 100 grafts are transplanted to each eyebrow,
but can be adjusted up or down depending upon the amount
of eyebrow to be restored.
Grafts are then atraumatically placed into the recipient
sites. The finest 1 hair grafts are reserved for the
edges, especially superior and lateral. Once transplanted,
no dressing or other special preparation is applied.
The patient may leave the office, wearing glasses if
desired, and careful washing may resume 2 days later.
Figure 3 illustrates the steps of an eyebrow restoration
procedure.
For the eyelashes, a topical anesthetic is applied to
the eye(s), and then a corneal eye protector is placed.
There are several methods of recipient site formation
and graft placement. In one, the hair thread is inserted
into the hole of a French needle, creating in essence
a suture. The needle is inserted in the eyelid skin
and brought out at the inferior tarsus border where
the eyelashes emerge. The root slides into the hole
following the needle, leaving the follicle in place
(Figure 4). Another technique is to make very tiny (21
gauge needle or 0.7 microblade) incisions along the
tarsal border, then insert the grafts retrograde as
with conventional hair graft placement. Finally, another
technique utilizes the placement of a one-follicle wide
strip of hair obtained from the sideburn region into
an undermined pocket of surrounding skin through an
incision made along the tarsal border. The graft is
secured in position by one or more 6-0 nylon sutures.(16)
One advantage of this technique, according to its authors,
is that it can be used for eyelash augmentation.
Because of the risk of trichiasis, procedures in the
lower eyelid must be done with caution, and the patient
advised as to this risk.
After Care
To avoid dislodging the grafts, for the first night
the patient can sleep wearing glasses or with the eye/brow
lightly patched. Ice applied for the first 48 hours
can prevent edema. Pain is managed with mild analgesics,
and most surgeons prescribe antibiotics. For the eyelashes,
an ophthalmic ointment or gel is recommended until the
crusts fall off.
Not infrequently, the transplanted hair grows immediately
after surgery. The patient must trim the eyebrow and
eyelash hairs every 2 to 4 weeks. An eyelash curler
can be helpful to control direction of hair growth.
For the eyebrows, training of the hairs to grow in the
desired direction can be undertaken by the application
of a gel or ointment for the first several months.
While eyebrow hairs have a survival rate typically 90%
or greater, eyelash grafts have a growth rate as low
as 50%. This loss is probably due to the extra manipulation
of the hairs, and can be compensated for by the transplanting
of additional grafts.
RECONSTRUCTION
OF THE SIDEBURN, MOUSTACHE AND BEARD
Sideburns represent the extension of scalp hair from
the temporal region to the pre-auricular region in women,
and connecting with the beard in men. The primary etiology
for absence of this facial hair in women is post-surgical,
following a facelift in which the vector of pull is
superior/posterior. This can usually be avoided by using
a facelift approach that extends the preauricular incision
from the helical root in an anterior horizontal direction
through the sideburn, rather than one that is in a more
superior vertical direction through the temporal scalp.
Because of its superiority in improving the cosmesis
of the lateral brow region, the latter orientation that
often results in hairline distortion is commonly chosen
by many plastic surgeons. For the beard and moustache
region, congenital absence or thinning are the most
common etiologies, while scarring from cleft lip surgery
or other trauma such as burns, are also seen.
A variety of surgical techniques have been described
for sideburn restoration.(15,24-38 ) and moustache/beard
restoration.(39-45) Our technique of choice is that
of transplanting with 1 and 2 hair follicular unit grafts
Surgical Technique
Preparation and Design
The design of the restoration is marked out on the patient.
For the sideburn, the key to achieving a natural appearance
is the use of the finest 1-hair grafts along the leading
anterior and inferior edges, where the direction of
growth is caudal and posterior, especially inferior
towards the tragus. (Please refer to the article on
hair transplantation in women which appears in this
Clincs) In the beard and moustache, the direction of
growth is essentially caudal, somewhat anterior along
the upper cheek region, with an angle closely parallel
to the skin.
Anesthesia is somewhat difficult to achieve, due to
extensive nerve supply of the facial region. Mental
and infraorbital nerve blocks only serve parts of the
face, requiring local anesthetic to be injected over
much of the rest of the areas to be transplanted.
Donor Material
The donor material comes from the occipital and, if
desired or needed, temporal scalp. A single fusiform
shaped strip is excised and the donor area reapproximated
with a 3-0 polypropylene suture. The size of the donor
strip is determined by the number of grafts to be transplanted.
Complete restoration of one sideburn is typically achieved
with 150 to 200 grafts, but this number can be larger
depending upon how high the defect extends. For the
beard and/or moustache, it is not uncommon to transplant
as many as 1600 to 1800 grafts. Natural results are
achieved with 1 and 2 hair grafts for these areas. In
many patients desiring beard/moustache restoration,
the concentration of grafts is usually desired in the
goatee (perioral) region. Attention must be paid as
to the natural concave curvature of the superior border
of the beard in the infra-oral region as it extends
caudally from the oral commissure in a vertical direction,
to a more horizontal direction along the cephalic edge
of the mental crease, returning to a vertical direction
in the central lower lip.
Recipient Sites and Graft Placement
Recipient sites are made with one of several instruments.
21 or 22 gauge needles or 0.8 to 1.0 mm microblades
are appropriate. As discussed above, the angle and direction
of the recipient sites are important in achieving a
natural appearing result. The microscopically dissected
grafts are then atraumatically implanted into the recipient
sites (see Figure 5).
After Care
Caution with the grafts must be taken the first 48 hours.
After this time, there is little risk of graft loss,
and gentle face washing may be resumed. All crusts should
fall off by 7 days, after which cautious shaving may
be performed.
CHEST HAIR TRANSPLANTATION
A particularly interesting area of transplantation,
given the recent trend towards the freedom from body
hair, is chest hair transplantation. It is our experience
that these patients have legitimate, realistic goals,
and are quite happy with their results.
Like with the eyebrow and eyelashes, the scalp hair
transplanted needs to be trimmed once or twice monthly.
The design of the restoration is such that the concentration
of hairs is along the central or sternal region, with
hairs extending outwards along the chest, often extending
lateral to the areola, and down around this important
anatomical landmark. At times patients may desire extension
of the restoration to the abdomen, to as low as the
pubis, where it is usually best to concentrate grafts
in the midline.
The direction of hair growth is typically medial and
inferior, with the most central hairs cross-hatching
with each other along the sternum so as to form a thicker
density. Peri-areolar, the direction of growth is usually
circular. The angle of growth is flat, parallel to the
chest skin. Figure 6 illustrates the overall pattern
of chest hair growth used for transplantation.
Perhaps the biggest challenge in chest hair transplantation
is achieving anesthesia. Because there is diffuse cutaneous
innervation that derives from deep and superficial nerves,
the entire chest region to be transplanted needs to
be injected superficially with local anesthesia. Because
of the large quantities of agent required, patients
will usually receive intravenous fluids, and areas are
injected regionally with intervals between injections
to avoid lidocaine toxicity. To reduce the discomfort
of injection, it is helpful to apply topical anesthetics
and ice, and, if desired, intravenous sedation is provided.
The donor area is the occipital and frequently temporal
scalp, to allow the taking of a large enough donor strip.
Typical procedures consist of 2000 or more 1 and 2 hair
follicular unit grafts, with smaller numbers utilized
for less coverage. Recipient sites are created with
20-degree needles or 1.0 to 1.1 mm chisel blades. The
grafts are then carefully inserted. Post-procedure care
is minimal. Showering is permitted after 48 hours, and
the crusts are expected to fall of within one week.
Hair growth typically resumes at 3 to 4 months. Trimming
of these original scalp hairs is usually needed once
or twice a month (see Figure 7).
RESTORATION OF
THE PUBIC ESCUTCHEON:
Tanaka in 1999 described the use of a free temporoparietal
fasciocutaneous flap for reconstructing the pubic region.(46)
However, since the beginning of hair transplantation,
Japanese surgeons have successfully used 1, 2, and 3
hair grafts for reconstruction of this region.(47,48)
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48. Karacaoglan N et al. Pubic hair reconstruction using
minigrafts and micrografts. Plast Recons Surg 2002.
109(3); 1200-1201.
Legends
Figure 1: The “ideal” feminine eyebrow.
Note the arched appearance with the peak at a point
directly above the lateral limbus.
Figure 2: The “ideal” male eyebrow. Note
the flatter appearance than the female version.
Figure 3: 30 year old female with significant loss of
eyebrow hair with etiology both congenital and secondary
to plucking. Before (A), before with the area of the
restoration marked out (B), immediately after (C), and
1 week after (D) 200 grafts.
Figure 4: Illustration of the needle insertion technique
in eyelid transplantation.
Figure 5: 38 year old male with congenital weakness
of beard hair. Before (A), intra-op (B), and 8 months
after (C) 1400 grafts. Note the flat angle of the blade
for the creation of recipient sites that will allow
the hairs to grow along the natural direction.
Figure 6: Illustration of the natural direction of chest
hair growth that can guide transplantation.
Figure 7: 34 year old male with congenital absence of
any significant chest hair. Before (A), intra-op (B),
and 8 months after (C) the third procedure. A total
of 6500 grafts were transplanted.
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